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Interspecies Chimerism with Mammalian Pluripotent Stem Cells

Interspecies Chimerism with Mammalian Pluripotent Stem Cells

Scientists have shown for the first time that undifferentiated human stem cells can be integrated into early embryos of both pigs and cattle. The construction of such interspecies embryos may represent an important development in the generation of organs for transplant.

Wu J, Platero-Luengo A, M Sakurai, et al. Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Cell 2017;168(3):473–486.