BLOOD: Humoral HLA sensitization matters in CBT outcome

In this issue of Blood, Cutler and colleagues present evidence that donor-specific anti-HLA antibodies are associated with graft failure in double umbilical cord blood transplantation (CBT).1 Engraftment of donor cells is the first important step in successful transplantation and, until recently, the causes of engraftment failure remained elusive.

http://bloodjournal.hematologylibrary.org/content/118/25/6482.full